| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Cerrados. |
|
Data corrente: |
12/12/2018 |
|
Data da última atualização: |
12/12/2018 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
PERIPOLLI, E.; METZGER, J.; LEMOS, M. V. A. de; STAFUZZA, N. B.; KLUSKA, S.; OLIVIERI, B. F.; FEITOSA, F. L. B.; BERTON, M. P.; LOPES, F. B.; MUNARI, D. P.; LOBO, R. B.; MAGNABOSCO, C. de U.; DI CROCE, F.; OSTERSTOCK, J.; DENISE, S.; PEREIRA, A. S. C.; BALDI, F. |
|
Afiliação: |
ELISA PERIPOLLI, UNESP; JULIA METZGER, University of Veterinary Medicine Hannover; MARCOS VINICIUS ANTUNES DE LEMOS, UNESP; NEDENIA BONVINOSTAFUZZA, UNESP; SABRINA KLUSKA, UNESP; BIANCA FERREIRA OLIVIERI, UNESP; FABIELI LOUISE BRAGA FEITOSA, UNESP; MARIANA PIATTO BERTON, UNESP; FERNANDO BRITO LOPES, UNESP; DANISIO PRADO MUNARI, UNESP; RAYSILDO BARBOSA LOBO, Associação Nacional de Criadores e Pesquisadores; CLAUDIO DE ULHOA MAGNABOSCO, CPAC; FERNANDO DI CROCE, Zoetis; JASON OSTERSTOCK, Zoetis; SUE DENISE, Zoetis; ANGELICA SIMONE CRAVO PEREIRA, USP; FERNANDO BALDI, UNESP. |
|
Título: |
Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits. |
|
Ano de publicação: |
2018 |
|
Fonte/Imprenta: |
BMC Genomics, v. 19, 680, 2018. |
|
DOI: |
https://dx.doi.org/10.1186%2Fs12864-018-5060-8 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pregnancy-associated glycoproteins genes (GO:0030163), and organism growth (GO:0040014) were described within the autozygotic islands. Conclusions Low FPED-FROH correlation estimates indicate that FPED is not the most suitable method for capturing ancient inbreeding when the pedigree does not extend back many generations and FROH should be used instead. Enriched terms (p < 0.01) suggest a strong selection for immune response. Non-overlapping islands within the lineages greatly explain the mechanism underlying selection for functionally important traits in Nellore cattle. MenosAbstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pr... Mostrar Tudo |
|
Palavras-Chave: |
Padroes ROH. |
|
Thesagro: |
Endogamia; Gado Nelore; Genética Animal; Genoma. |
|
Thesaurus Nal: |
Homozygosity. |
|
Categoria do assunto: |
G Melhoramento Genético |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/188276/1/12864-2018-Article-5060-APAGAR.pdf
|
|
Marc: |
LEADER 03204naa a2200397 a 4500
001 2101339
005 2018-12-12
008 2018 bl uuuu u00u1 u #d
024 7 $ahttps://dx.doi.org/10.1186%2Fs12864-018-5060-8$2DOI
100 1 $aPERIPOLLI, E.
245 $aAutozygosity islands and ROH patterns in Nellore lineages$bevidence of selection for functionally important traits.$h[electronic resource]
260 $c2018
520 $aAbstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels for classical standards, with an average value of 7.15% (178.70 Mb). The average of FPED and FROH, and their correlations (− 0.05 to 0.26) were low. Estimates of correlation between FGRM-FPED was zero, while the correlation (− 0.01 to − 0.07) between FGRM-FROH decreased as a function of ROH length, except for FROH > 8Mb (− 0.03). Overall, inbreeding coefficients were not high for the genotyped animals. Autozygosity islands were evident across the genome (n = 62) and their genomic location did not largely differ within lineages. Enriched terms (p < 0.01) associated with defense response to bacteria (GO:0042742), immune complex reaction (GO:0045647), pregnancy-associated glycoproteins genes (GO:0030163), and organism growth (GO:0040014) were described within the autozygotic islands. Conclusions Low FPED-FROH correlation estimates indicate that FPED is not the most suitable method for capturing ancient inbreeding when the pedigree does not extend back many generations and FROH should be used instead. Enriched terms (p < 0.01) suggest a strong selection for immune response. Non-overlapping islands within the lineages greatly explain the mechanism underlying selection for functionally important traits in Nellore cattle.
650 $aHomozygosity
650 $aEndogamia
650 $aGado Nelore
650 $aGenética Animal
650 $aGenoma
653 $aPadroes ROH
700 1 $aMETZGER, J.
700 1 $aLEMOS, M. V. A. de
700 1 $aSTAFUZZA, N. B.
700 1 $aKLUSKA, S.
700 1 $aOLIVIERI, B. F.
700 1 $aFEITOSA, F. L. B.
700 1 $aBERTON, M. P.
700 1 $aLOPES, F. B.
700 1 $aMUNARI, D. P.
700 1 $aLOBO, R. B.
700 1 $aMAGNABOSCO, C. de U.
700 1 $aDI CROCE, F.
700 1 $aOSTERSTOCK, J.
700 1 $aDENISE, S.
700 1 $aPEREIRA, A. S. C.
700 1 $aBALDI, F.
773 $tBMC Genomics$gv. 19, 680, 2018.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Cerrados (CPAC) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
|
Data corrente: |
03/01/2020 |
|
Data da última atualização: |
09/01/2024 |
|
Tipo da produção científica: |
Artigo em Anais de Congresso |
|
Autoria: |
TADINI, A.; MORAIS, C. P.; BERNARDI, A. C. de C.; FALVO, M.; BRUNO, O. M.; MOUNIER, S.; MARTIN NETO, L.; MILORI, D. M. B. P.; GUIMARÃES, F. E. G. |
|
Afiliação: |
Amanda Maria Tadini, FAPESP; Carla Pereira de Morais, USP; ALBERTO CARLOS DE CAMPOS BERNARDI, CPPSE; Mauricio Falvo, USP; Odemir Martinez Bruno, USP; Stephane Mounier, University of Toulon; LADISLAU MARTIN NETO, CNPDIA; DEBORA MARCONDES BASTOS PEREIRA, CNPDIA; Francisco Eduardo Gontijo Guimaraes, USP. |
|
Título: |
Caracterização direta da matéria orgânica em solos e sedimentos por microscopia confocal e imagem de tempo de vida. |
|
Ano de publicação: |
2019 |
|
Fonte/Imprenta: |
In: SIMPÓSIO NACIONAL DE INSTRUMENTAÇÃO AGROPECUÁRIA, 4., 2019, São Carlos, SP. Anais... São Carlos, SP: Embrapa Instrumentação, 2019. |
|
Páginas: |
508-512 |
|
ISSN: |
2358-9132 |
|
Idioma: |
Português |
|
Notas: |
Editores: Paulino Ribeiro Villas-Boas, Maria Alice Martins, Débora Marcondes Bastos Pereira Milori, Ladislau Matin Neto. IV SIAGRO. |
|
Conteúdo: |
A presente contribuição pretende mostrar que Microscopia Confocal (MC) por varredura pode ser usada como técnica de fluorescência não destrutiva capaz de caracterizar a matéria orgânica (MO) diretamente em solos e em sedimentos sem a preparação prévia das amostras e o uso de extração ou fracionamento químico de seus componentes. |
|
Palavras-Chave: |
Agregados moleculares; ILPF; Microscopia confocal; Sedimentos. |
|
Thesagro: |
Matéria Orgânica; Solo. |
|
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
|
Marc: |
LEADER 01460nam a2200313 a 4500
001 2118017
005 2024-01-09
008 2019 bl uuuu u01u1 u #d
022 $a2358-9132
100 1 $aTADINI, A.
245 $aCaracterização direta da matéria orgânica em solos e sedimentos por microscopia confocal e imagem de tempo de vida.$h[electronic resource]
260 $aIn: SIMPÓSIO NACIONAL DE INSTRUMENTAÇÃO AGROPECUÁRIA, 4., 2019, São Carlos, SP. Anais... São Carlos, SP: Embrapa Instrumentação$c2019
300 $a508-512
500 $aEditores: Paulino Ribeiro Villas-Boas, Maria Alice Martins, Débora Marcondes Bastos Pereira Milori, Ladislau Matin Neto. IV SIAGRO.
520 $aA presente contribuição pretende mostrar que Microscopia Confocal (MC) por varredura pode ser usada como técnica de fluorescência não destrutiva capaz de caracterizar a matéria orgânica (MO) diretamente em solos e em sedimentos sem a preparação prévia das amostras e o uso de extração ou fracionamento químico de seus componentes.
650 $aMatéria Orgânica
650 $aSolo
653 $aAgregados moleculares
653 $aILPF
653 $aMicroscopia confocal
653 $aSedimentos
700 1 $aMORAIS, C. P.
700 1 $aBERNARDI, A. C. de C.
700 1 $aFALVO, M.
700 1 $aBRUNO, O. M.
700 1 $aMOUNIER, S.
700 1 $aMARTIN NETO, L.
700 1 $aMILORI, D. M. B. P.
700 1 $aGUIMARÃES, F. E. G.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
